Monotherapie Phase II

ERA-Studie:

Genovese MC, Bathon JM, Fleischmann RM, Moreland LW, Martin RW, Whitmore JB, Tsuji WH, Leff JA.
Longterm safety, efficacy, and radiographic outcome with etanercept treatment in patients with early rheumatoid arthritis.
J Rheumatol. 2005 Jul;32(7):1232-42.

Bathon JM, Genovese MC:
The Early Rheumatoid Arthritis (ERA) trial comparing the efficacy and safety of etanercept and methotrexate.
Clin Exp Rheumatol. 2003 Sep-Oct;21(5 Suppl 31):S195-7. 

Genovese MC, Bathon JM, Martin RW, Fleischmann RM, Tesser JR, Schiff MH, Keystone EC, Wasko MC, Moreland LW, Weaver AL, Markenson J, Cannon GW, Spencer-Green G, Finck BK.
Etanercept versus methotrexate in patients with early rheumatoid arthritis: two-year radiographic and clinical outcomes.
Arthritis Rheum. 2002 Jun;46(6):1443-50

Bathon JM, Martin RW, Fleischmann RM, Tesser JR, Schiff MH, Keystone EC, Genovese MC, Wasko MC, Moreland LW, Weaver AL, Markenson J, Finck BK.
A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis et al.
N Engl J Med 2000; 343: 1586-1593

Moreland LW, Baumgartner SW, Schiff MH et al.
Treatment of rheumatoid arthritis with a recombinant human tumor necrosis factor receptor (p75)-Fc fusion protein.
N Engl J Med 1997; 337: 141-147